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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK14
All Species:
23.94
Human Site:
S375
Identified Species:
40.51
UniProt:
O94921
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94921
NP_036527.1
469
53057
S375
P
E
R
F
T
L
Y
S
S
K
N
L
R
Q
A
Chimpanzee
Pan troglodytes
XP_519189
469
53035
S375
P
E
R
F
T
L
Y
S
S
K
S
L
R
Q
A
Rhesus Macaque
Macaca mulatta
XP_001102520
469
53072
S375
P
E
R
F
T
L
Y
S
S
K
N
L
R
Q
A
Dog
Lupus familis
XP_532455
469
53036
S375
P
E
R
F
T
L
Y
S
S
K
N
L
R
Q
A
Cat
Felis silvestris
Mouse
Mus musculus
O35495
469
52977
S375
P
E
R
F
T
V
Y
S
S
K
S
L
R
Q
A
Rat
Rattus norvegicus
O35831
523
59414
K429
F
K
N
Y
N
F
P
K
Y
K
P
Q
P
L
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516045
337
37621
H244
I
H
Q
R
Y
I
L
H
R
D
L
K
P
Q
N
Chicken
Gallus gallus
XP_418647
773
84016
S679
P
E
R
F
T
Q
Y
S
P
K
N
L
R
Q
A
Frog
Xenopus laevis
Q6DJM7
435
49211
G341
P
E
R
F
T
L
Y
G
P
K
N
L
R
Q
A
Zebra Danio
Brachydanio rerio
Q1RLU9
418
47889
P325
E
W
F
L
P
C
K
P
Q
Q
F
R
D
V
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523904
522
59750
T421
K
I
F
K
L
L
G
T
P
T
E
D
T
W
P
Honey Bee
Apis mellifera
XP_624994
494
56118
H395
E
T
W
P
G
V
T
H
L
P
G
Y
K
P
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P24100
294
34012
K201
F
A
E
M
I
S
Q
K
P
L
F
P
G
D
S
Baker's Yeast
Sacchar. cerevisiae
P17157
305
34888
T212
G
K
P
L
F
P
G
T
N
D
E
E
Q
L
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
99.7
99.1
N.A.
98.5
43
N.A.
60.7
58.5
85.2
51.5
N.A.
48.4
50
N.A.
N.A.
Protein Similarity:
100
99.5
99.7
100
N.A.
99.3
59
N.A.
63.3
59.5
89.3
63.1
N.A.
61.2
63.3
N.A.
N.A.
P-Site Identity:
100
93.3
100
100
N.A.
86.6
6.6
N.A.
6.6
86.6
86.6
0
N.A.
6.6
0
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
20
N.A.
20
86.6
86.6
6.6
N.A.
13.3
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.7
28.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
42.8
43.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
50
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
15
0
8
8
8
0
% D
% Glu:
15
50
8
0
0
0
0
0
0
0
15
8
0
0
0
% E
% Phe:
15
0
15
50
8
8
0
0
0
0
15
0
0
0
0
% F
% Gly:
8
0
0
0
8
0
15
8
0
0
8
0
8
0
0
% G
% His:
0
8
0
0
0
0
0
15
0
0
0
0
0
0
8
% H
% Ile:
8
8
0
0
8
8
0
0
0
0
0
0
0
0
8
% I
% Lys:
8
15
0
8
0
0
8
15
0
58
0
8
8
0
8
% K
% Leu:
0
0
0
15
8
43
8
0
8
8
8
50
0
15
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
8
0
0
0
8
0
36
0
0
0
8
% N
% Pro:
50
0
8
8
8
8
8
8
29
8
8
8
15
8
8
% P
% Gln:
0
0
8
0
0
8
8
0
8
8
0
8
8
58
0
% Q
% Arg:
0
0
50
8
0
0
0
0
8
0
0
8
50
0
0
% R
% Ser:
0
0
0
0
0
8
0
43
36
0
15
0
0
0
8
% S
% Thr:
0
8
0
0
50
0
8
15
0
8
0
0
8
0
0
% T
% Val:
0
0
0
0
0
15
0
0
0
0
0
0
0
8
0
% V
% Trp:
0
8
8
0
0
0
0
0
0
0
0
0
0
8
8
% W
% Tyr:
0
0
0
8
8
0
50
0
8
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _